Phd thesis antimicrobial

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Phd thesis antimicrobial in 2021

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Phd thesis on antimicrobial activity of medicinal plants

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What was the purpose of the PhD project?

An additional aim of the PhD project was to compare antimicrobial and antibiofilm properties of analogues peptides and peptoids toward E. coli.

Why is it important to develop novel antimicrobial agents?

Therefore, it is urgent to develop novel antimicrobial agents able to prevent and treat biofilms associated infections. Antimicrobial peptides (AMPs) are considered promising tools for defeating both acute and chronic bacterial infections and have a lower rate of resistance development than the antibiotics.

Who are the authors of the PhD thesis?

I am much indebted to Dr. Biljana Moisoska, Prof. Kornelius Zeth, Dr. Thomas Thyge Thomsen and Dr. Godefroid Charbon for offering me help and advices whenever needed during my experimental work.

Why are biofilms a defense mechanism against antimicrobial agents?

The ability of bacteria to form biofilms constitutes one of the possible defense mechanisms from antimicrobial agents. Biofilms formation on medical devices, as indwelling catheters, and in infected wounds leads to chronic and life-threatening infections that are recalcitrant to antibiotics treatment.

Last Update: Oct 2021

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