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Table of contents
- Parathyroid hormone thesis in 2021
- Elevated parathyroid hormone
- High parathyroid hormone means
- Parathyroid hormone levels chart
- Parathyroid hormone thesis 05
- Parathyroid hormone thesis 06
- Parathyroid hormone thesis 07
- Parathyroid hormone thesis 08
Parathyroid hormone thesis in 2021
Elevated parathyroid hormone
High parathyroid hormone means
Parathyroid hormone levels chart
Parathyroid hormone thesis 05
Parathyroid hormone thesis 06
Parathyroid hormone thesis 07
Parathyroid hormone thesis 08
What are the two umbrella categorizations of parathyroid dysfunction?
The 2 umbrella categorizations of parathyroid dysfunctions are hyperparathyroidism and hypoparathyroidism. The inappropriately high secretion of PTH is classified as hyperparathyroidism, while the inappropriately low secretion of PTH is designated as hyperparathyroidism.
How is the structure of parathyroid hormone determined?
Parathyroid hormone is a polypeptide that is synthesized and cleaved into an active form within the parathyroid gland. The initial structure formed is a pre-pro-PTH, a 115 amino acid polypeptide that is cleaved to form pro-PTH comprised of 90 amino acids.
Where does the parathyroid gland secrete vitamin D3?
PTH facilitates the synthesis of active vitamin D, calcitriol (1,25-dihydroxycholecalciferol, or vitamin D3) in the kidneys. In conjunction with calcitriol, PTH regulates calcium and phosphate. PTH effects are present in the bones, kidneys, and small intestines. As serum calcium levels drop, the secretion of PTH by the parathyroid gland increases.
How does parathyroid hormone affect calcium reabsorption?
Circulating parathyroid hormone targets the distal convoluted tubule and collecting duct, directly increasing calcium reabsorption. Parathyroid hormone decreases phosphate reabsorption at the proximal convoluted tubule. Phosphate ions in the serum form salts with calcium that are insoluble, resulting in a decreased plasma calcium.
Last Update: Oct 2021
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